A First Cure for Syphilis

概述-历史记载    Introduction - Historical Notes

首次治愈梅毒

数个世纪以来,曾用水银(以其药膏、口服药物和蒸汽浴的剂方)治疗过梅毒。19世纪期间,较有用的碘化钾开始被运用,然而即使这种办法也大同小异。那时,真正有效的和无损健康的治疗方法简直就不存在。不仅千千万万的平头百姓,而且历史上的许多名人也死于梅毒。最终,在20世纪的早期,德国科学家破译出了梅毒有效治疗的基本原理。

1905年,F.施奥丁恩(Fritz Schaudinn,1871-1906)发现了梅毒致病的罪魁祸首——苍白螺旋体(treponema pallidum)。

次年的1906年,瓦塞尔曼(August von Wassermann,1866-1925)改进了至今仍以他的名字命名的实验。这个叫“瓦塞尔曼实验”(“Wassermann test”)可以让我们早期发现梅毒感染。

最后,到了1910年,德国医学家保罗•厄勒克Paul Ehrlich,1958-1915)和他的日本助手山下黑罗(Sachahiro Hata,1873-1938)经过数百次的实验,拿出了第一个有效的治疗方案,他们称之为“撒尔佛散(Salvarsan)”的砷化合剂。后来,厄勒克发展出一种改良的剂方,称为“撒尔佛散(Neosalvarsan)”。不久,厄勒克以梅毒的征服者而声名大噪。为在免疫学上的贡献,他赢得了1908的诺贝尔医学奖。

F.施奥丁恩
Fritz Schaudinn
(1871-1906)

A.瓦塞尔曼
August von Wassermann
(1866-1925)

保罗•厄勒克
Paul Ehrlich (1854-1915)
山下黑罗
and Sachahiro Hata (1873-1938)

A First Cure for Syphilis

For centuries, syphilis was treated with mercury (in the form of ointments, oral medication, and vapor baths). In the course of the 19th century, the more serviceable potassium iodide came to be used, but even this did not make a real difference. A truly effective and healthy treatment simply did not exist. Not only thousands of ordinary people, but many famous historical personalities died of syphilis. Eventually, the basis for an effective treatment was laid by German scientists in the early 20th century.
In 1905,
Fritz Schaudinn discovered the causative agent of syphilis, the bacterium treponema pallidum.
Only one year later, in 1906,
August von Wassermann developed the test which is still named after him. This “Wassermann test” allowed the early discovery of a syphilitic infection.
Finally, in 1910, the German medical researcher
Paul Ehrlich and his Japanese assistant Sachahiro Hata, after hundreds of trials, came up with the first effective cure, an arsenic compound they called “Salvarsan”. Later, Ehrlich developed an improved version called “Neosalvarsan”. Soon he was widely celebrated as the conqueror of syphilis. For his work in immunology, Ehrlich had already received a Nobel Prize for Medicine in 1908.
 

[Course 4] [Description] [How to use it] [Introduction] [Terms] [General Description] [Historical Notes] [Curable STDs] [Incurable STDs] [STD Prevention] [Additional Reading] [Examination]